Nutrition of the intervertebral disc: solute transport and metabolism.

  title={Nutrition of the intervertebral disc: solute transport and metabolism.},
  author={Sten H Holm and Alice Maroudas and Jill P G Urban and Gunnar Selstam and Alf Nachemson},
  journal={Connective tissue research},
  volume={8 2},
The metabolism of the canine nucleus pulposus was investigated at different oxygen tensions. It was found that even at high oxygen tensions the metabolism is mainly anaerobic, only approximately 1.5% of the glucose being converted to carbon dioxide. The concentration dependence of oxygen consumption is limited to very low oxygen tensions. Values of oxygen consumption and lactic acid production were used to calculate the concentration profiles of these substances within the nucleus pulposus… CONTINUE READING

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