Nutrition and disease: challenges of research design.

  title={Nutrition and disease: challenges of research design.},
  author={Norman J. Temple},
  volume={18 4},
This review discusses research methodology in the relation between diet and disease. Medical research can be divided into two types: complex research (the detailed study of disease mechanisms using such methods as biochemistry and molecular genetics) and simple research (the investigation of the factors that cause or prevent disease using methods such as epidemiology, intervention trials, and analagous studies on animals). Although complex research has received the bulk of resources, the large… CONTINUE READING


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