Nutrient sensing and the circadian clock.

  title={Nutrient sensing and the circadian clock.},
  author={Clara Bien Peek and Kathryn Moynihan Ramsey and Biliana Marcheva and Joseph Bass},
  journal={Trends in endocrinology and metabolism: TEM},
  volume={23 7},
The circadian system synchronizes behavioral and physiologic processes with daily changes in the external light-dark cycle, optimizing energetic cycles with the rising and setting of the sun. Molecular clocks are organized hierarchically, with neural clocks orchestrating the daily switch between periods of feeding and fasting, and peripheral clocks generating 24h oscillations of energy storage and utilization. Recent studies indicate that clocks respond to nutrient signals and that a high-fat… CONTINUE READING
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