Nutrient restriction during early life reduces cell proliferation in the hippocampus at adulthood but does not impair the neuronal differentiation process of the new generated cells.

@article{Matos2011NutrientRD,
  title={Nutrient restriction during early life reduces cell proliferation in the hippocampus at adulthood but does not impair the neuronal differentiation process of the new generated cells.},
  author={Rhowena Jane Barbosa Matos and Ricardo Orozco-Sol{\'i}s and Sandra Lopes de Souza and Raul Manh{\~a}es-de-Castro and Francisco Bola{\~n}os-Jim{\'e}nez},
  journal={Neuroscience},
  year={2011},
  volume={196},
  pages={16-24}
}
Maternal malnutrition results in learning deficits and predisposition to anxiety and depression in the offspring that extend into adulthood. At the cellular level, learning and memory rely on the production of new neurons in the dentate gyrus (DG) of the hippocampus, and hippocampal neurogenesis has been associated with the etiology and treatment of depression, but whether adult neurogenesis is affected by malnutrition during early life is not known. To investigate the effects of perinatal… CONTINUE READING
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