Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response.

@article{Zinke2002NutrientCO,
  title={Nutrient control of gene expression in Drosophila: microarray analysis of starvation and sugar-dependent response.},
  author={Ingo Zinke and Christina S. Schuetz and Joerg D Katzenberger and Matthias R. Bauer and Michael J Pankratz},
  journal={The EMBO journal},
  year={2002},
  volume={21 22},
  pages={6162-73}
}
We have identified genes regulated by starvation and sugar signals in Drosophila larvae using whole-genome microarrays. Based on expression profiles in the two nutrient conditions, they were organized into different categories that reflect distinct physiological pathways mediating sugar and fat metabolism, and cell growth. In the category of genes regulated in sugar-fed, but not in starved, animals, there is an upregulation of genes encoding key enzymes of the fat biosynthesis pathway and a… CONTINUE READING
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