Nutraceutical effects of branched-chain amino acids on skeletal muscle.

@article{Shimomura2006NutraceuticalEO,
  title={Nutraceutical effects of branched-chain amino acids on skeletal muscle.},
  author={Yoshiharu Shimomura and Yuko Yamamoto and Gustavo Cancian Bajotto and Juichi Sato and Taro Murakami and Noriko Shimomura and Hisamine Kobayashi and Kazunori Mawatari},
  journal={The Journal of nutrition},
  year={2006},
  volume={136 2},
  pages={
          529S-532S
        }
}
BCAA catabolism in skeletal muscle is regulated by the branched-chain alpha-keto acid dehydrogenase (BCKDH) complex, located at the second step in the BCAA catabolic pathway. The activity of the BCKDH complex is regulated by a phosphorylation/dephosphorylation cycle. Almost all of BCKDH complex in skeletal muscle under normal and resting conditions is in an inactive/phosphorylated state, which may contribute to muscle protein synthesis and muscle growth. Exercise activates the muscle BCKDH… CONTINUE READING

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