Nutmeg intoxication in Texas, 1998–2004

  title={Nutmeg intoxication in Texas, 1998–2004},
  author={Mathias B. Forrester},
  journal={Human and Experimental Toxicology},
  pages={563 - 566}
  • M. Forrester
  • Published 2005
  • Medicine
  • Human and Experimental Toxicology
Nutmeg is a spice that contains volatile oils comprised of alkyl benzene derivatives (myristicin, elemicin, safrole, etc.), terpenes and myristic acid. Nutmeg has a long history of abuse. This study describes the nutmeg ingestion calls received by Texas poison centers from 1998 to 2004. There were 17 calls involving nutmeg ingestion, of which 64.7% involved intentional abuse. When abuse and non-abuse ingestions were compared, abuse ingestions were more likely to involve males (100 versus 66.7… Expand
The spice of life: An analysis of nutmeg exposures in California
Although nutmeg exposure is uncommonly encountered, clinical effects from ingestion can be significant and can require medical intervention, and clinically significant effects were common, life-threatening toxicity and death did not occur in this series. Expand
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A detailed review of myristicin is reported, which is responsible for hallucinogenic effects, which induced by the consumption of nutmeg due to its metabolism structure of 3-methoxy-4,5-methylendioxyamphetamine (MMDA), and its effects on health problems related to brain problem. Expand
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An unexpected percentage of unintentional exposures in juveniles under the age of 13, out of the total exposures to nutmeg, are shown in this study. Expand
Determination of myristicin in commonly spices applying SPE/GC.
  • A. Dawidowicz, M. Dybowski
  • Chemistry, Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
  • 2012
The presented analytical approach constitutes a substantial improvement on previously reported methods for myristicin analysis and seems to be the method of choice for determining the amount of the compound in spices containing nutmeg. Expand
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It is reasonably speculates that nutmeg exposure may cause liver damage and affect liver function depending on the dose and duration of exposure. Expand
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Nutmeg is abused because myristicin has psychotropic and hallucinogenic properties [5]. Human studies indicate that myristicin at a dose of 6–7 mg kg –1 body weight can have psychopharmacologicalExpand
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This diagnosis should be considered in patients presenting with an acute psychotic break accompanied by symptoms resembling an anticholinergic toxic episode, once other life-threatening conditions have been ruled out. Expand
Nutmeg (myristicin) poisoning--report on a fatal case and a series of cases recorded by a poison information centre.
In the present case, myristicin was detected for the first time in the postmortal serum of a 55-year-old woman, and because also flunitrazepam was found, death had probably been due to the combined toxic effect of both substances. Expand
Toxicology of Nutmeg Abuse
A 13-year-old female ingested 15–24 g of nutmeg over a 3-hour period and smoked and shared 2 joints of marijuana and developed bizarre behavior and visual, auditory, and tactile hallucinations. Expand
Toxicological evaluation of myristicin.
Intake estimations indicate that nonalcoholic drinks may be the most important single source of myristicin intake, and it seems unlikely that the intake from essential oils and spices in food, estimated to a few mg per person and day, would cause adverse effects in humans. Expand
Acute nutmeg poisoning
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  • Medicine
  • European journal of emergency medicine : official journal of the European Society for Emergency Medicine
  • 2004
We present a case of acute nutmeg poisoning in a 16-year-old youth who had ingested the substance for recreational purposes. He developed a number of neurological symptoms and signs along withExpand
Constituents of aromatic plants: elemicin.
Elemicin did induce UDS in hepatocytes from male rats, and studies on carcinogenicity were negative, but the 1'-hydroxy-metabolite of elemicin gave positive and negative results. Expand
Nutmeg intoxication in pregnancy. A case report.
  • G. Lavy
  • Medicine
  • The Journal of reproductive medicine
  • 1987
A case of acute anticholinergic hyperstimulation in a pregnant woman was associated with excessive ingestion of nutmeg, with a special emphasis on the pregnant state. Expand
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Nutmeg poisoning is rare but probably underreported and should be considered in recreational substance users with acute psychotic symptoms as well as central nervous system neuromodulatory signs thatExpand