Nuphar Dimers: Crouching Sulfur, Hidden Reactivity

  title={Nuphar Dimers: Crouching Sulfur, Hidden Reactivity},
  author={L. A. Marcaurelle and M. Mulvihill},
  journal={ACS Central Science},
  pages={367 - 369}
Hidden electrophilicity in Nuphar alkaloids is responsible for their impressive bioactivity, report Shenvi and colleagues. 
4 Citations
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An eight step, asymmetric synthesis of a dimeric thiaspirane nuphar alkaloid from 3-methyl-2-cyclo-pentenone is reported, and the distribution of products that arise from spontaneous dimerization points to a more complex biosynthesis. Expand
Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes
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Potent anti-metastatic activity of dimeric sesquiterpene thioalkaloids from the rhizome of Nuphar pumilum.
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the rhizome of Nuphar pumilum
  • Bioorg. Med. Chem. Lett
  • 2003