Corpus ID: 100115832

Nunes KP, Toque HA, Caldwell RB, Caldwell RW, Webb RC. Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice. J Sex Med 2011;8:3335-44.

@inproceedings{William2015NunesKT,
  title={Nunes KP, Toque HA, Caldwell RB, Caldwell RW, Webb RC. Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice. J Sex Med 2011;8:3335-44.},
  author={R. William},
  year={2015}
}

References

SHOWING 1-2 OF 2 REFERENCES
Extracellular signal-regulated kinase (ERK) inhibition decreases arginase activity and improves corpora cavernosal relaxation in streptozotocin (STZ)-induced diabetic mice.
TLDR
It is hypothesized that inhibition of ERK by ERK inhibitor PD98059 decreases AA and thus improves cavernosal relaxation in streptozotocin-diabetic mice and protects against ED caused by diabetes. Expand
FK506 neuroprotection after cavernous nerve injury is mediated by thioredoxin and glutathione redox systems.
TLDR
The neuroprotective effect of FK in preserving EF after CNI involves antioxidative/nitrosative and antiapoptotic mechanisms mediated, to some extent, by Trx and GSH systems. Expand