Numerical studies of the frequency trajectories in the process of fixation of null genes at duplicated loci1

@article{Maruyama1981NumericalSO,
  title={Numerical studies of the frequency trajectories in the process of fixation of null genes at duplicated loci1},
  author={Takeo Maruyama and Naoyuki Takahata},
  journal={Heredity},
  year={1981},
  volume={46},
  pages={49-57}
}
SummaryA new numerical method, based on the stochastic differential equations, has been applied to the problem of the fixation of null alleles at duplicated loci. The results reported here were obtained under the assumption that individuals carrying homozygous null genes at both of the duplicated loci are lethal, but all the other genotypes are normal. The mean and median time for null alleles to fix can vary from 2N to 100N or more, depending on the mutation rate and the population size, where… CONTINUE READING