Numerical simulation of molecular uptake via electroporation.

  title={Numerical simulation of molecular uptake via electroporation.},
  author={Jianbo Li and Hao Lin},
  volume={82 1},
A numerical study of electroporation-mediated molecular delivery is presented. The model consists of the Nernst-Planck equations for species transport, coupled with an asymptotic Smoluchowski equation for membrane permeabilization. The transfer of calcium ions into a Chinese Hamster Ovary cell is simulated. The results reveal important physical insights. First, for this particular case, ion electrophoresis plays an important role, and is an order of magnitude faster than free diffusion on a… CONTINUE READING

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