Numerical reconstruction of gene expression measurements from mixed cell populations

Abstract

We propose a procedure for numerically decomposing gene from a heterogeneous cell population into components that can be attributed to pure subpopulations of cells. expiession me&urements obtained from a mixed cenpbpulation into estimates of the expression levels for the biologically distinct components of the mixture. The motivating a p plication is the… (More)
DOI: 10.1109/ISBI.2002.1029189

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