Numerical model for calculation of apparent diffusion coefficients (ADC) in permeable cylinders--comparison with measured ADC in spinal cord white matter.

@article{Ford1997NumericalMF,
  title={Numerical model for calculation of apparent diffusion coefficients (ADC) in permeable cylinders--comparison with measured ADC in spinal cord white matter.},
  author={Jonathan Ford and David B. Hackney},
  journal={Magnetic resonance in medicine},
  year={1997},
  volume={37 3},
  pages={387-94}
}
We have implemented a numerical method for calculation of the apparent diffusion coefficient (ADC) in spinal cord injury, which takes into account the distribution of axon diameters and permeability found in spinal cord white matter, as well as relative axonal volume. We propose a procedure for determining the status of axonal integrity from measured ADC values. These methods have been applied to a well characterized rat spinal cord injury model, affording a prediction of the increase in axonal… CONTINUE READING