Numerical model and experimental validation of microcarrier motion in a rotating bioreactor.

@article{Pollack2000NumericalMA,
  title={Numerical model and experimental validation of microcarrier motion in a rotating bioreactor.},
  author={S R Pollack and David F. Meaney and Elliot M. Levine and Mitchell Litt and Eric D Johnston},
  journal={Tissue engineering},
  year={2000},
  volume={6 5},
  pages={519-30}
}
The equations of motion for microcarriers in a rotating bioreactor have been formulated and trajectories obtained using numerical techniques. An imaging system was built to validate the results by direct observation of microcarrier trajectories in the rotating frame of reference. The microcarrier motion observed by this imaging system was in excellent agreement with the numerical predictions of that motion. In the rotating frame of reference, microcarriers with density greater than the… CONTINUE READING

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