Numerical investigation of dynamic microorgan devices as drug screening platforms. Part I: Macroscale modeling approach & validation.

Abstract

The dynamic nature of in vitro drug metabolism models demands reliable numerical tools to determine key design parameter values towards high-fidelity cell-based platforms of in vivo drug metabolism. This paper represents the first of a two-part model-based investigation of a 3D dynamic microorgan device (DMD). The prescribed tissue model in this paper is… (More)
DOI: 10.1002/bit.25822

Topics

Figures and Tables

Sorry, we couldn't extract any figures or tables for this paper.

Slides referencing similar topics