Numerical abnormalities of chromosome 7 in human prostate cancer detected by fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with centromere-specific DNA probes.

@article{Zitzelsberger1994NumericalAO,
  title={Numerical abnormalities of chromosome 7 in human prostate cancer detected by fluorescence in situ hybridization (FISH) on paraffin-embedded tissue sections with centromere-specific DNA probes.},
  author={Horst F. Zitzelsberger and Sandor Sz{\"u}cs and Heinz Ulrich G. Weier and L. Lehmann and Herbert Braselmann and Stephen Enders and Andreas Schilling and J{\"u}rgen Breul and Heinz Hoefler and Manfred Bauchinger},
  journal={The Journal of pathology},
  year={1994},
  volume={172 4},
  pages={325-35}
}
Fluorescence in situ hybridization (FISH) using chromosome-specific alpha-satellite DNA probes for chromosomes 7, 8, and 12 was performed on paraffin-embedded tissue sections and touch imprint preparations of 53 cases of human prostate cancer. Subsequent haematoxylin and eosin (H & E) staining of the hybridized tissue sections allowed unambiguous assignment of hybridization signals either to tumour or to non-tumorous parenchyma. Fifty-three cases of human prostate cancer were evaluated for… CONTINUE READING

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