Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis.

@article{Wang2010NullGO,
  title={Null genotypes of GSTM1 and GSTT1 contribute to hepatocellular carcinoma risk: evidence from an updated meta-analysis.},
  author={Bin Wang and Gang Huang and Dan Wang and Ai-jun Li and Zhipeng Xu and Ran Dong and Deqiang Zhang and Wei-ping Zhou},
  journal={Journal of hepatology},
  year={2010},
  volume={53 3},
  pages={508-18}
}
BACKGROUND & AIMS Studies investigating the associations between glutathione S-transferase (GST) genetic polymorphisms and hepatocellular carcinoma (HCC) risk have reported controversial results. Thus, a meta-analysis was performed to clarify the effects of GSTM1 and GSTT1 polymorphisms on HCC risk. METHODS We identified 132 relevant records through a literature search up to November 22, 2009, and 24 individual case-control studies from 23 publications were finally included, involving a total… CONTINUE READING