Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin

@inproceedings{Shan2009NudelAF,
  title={Nudel and FAK as Antagonizing Strength Modulators of Nascent Adhesions through Paxillin},
  author={Yongli Shan and Lihou Yu and Yan Li and Youdong Pan and Qiangge Zhang and Fubin Wang and Jianfeng Chen and Xueliang Zhu},
  booktitle={PLoS biology},
  year={2009}
}
Adhesion and detachment are coordinated critical steps during cell migration. Conceptually, efficient migration requires both effective stabilization of membrane protrusions at the leading edge via nascent adhesions and their successful persistence during retraction of the trailing side via disruption of focal adhesions. As nascent adhesions are much smaller in size than focal adhesions, they are expected to exhibit a stronger adhesivity in order to achieve the coordination between cell front… CONTINUE READING