Nucleus-vacuole junctions and piecemeal microautophagy of the nucleus in S. cerevisiae.

@article{Kvam2007NucleusvacuoleJA,
  title={Nucleus-vacuole junctions and piecemeal microautophagy of the nucleus in S. cerevisiae.},
  author={Erik Kvam and David S. Goldfarb},
  journal={Autophagy},
  year={2007},
  volume={3 2},
  pages={85-92}
}
Various modes of autophagy conspire to degrade virtually every compartment of the eukaryotic cell. In Saccharomyces cerevisiae, a process called "piecemeal microautophagy of the nucleus" (PMN) even pinches off and degrades nonessential portions of the nucleus. PMN is a constitutive process induced to high levels by starvation or rapamycin, an inhibitor of TOR kinase. PMN occurs at nucleus-vacuole (NV) junctions, which are Velcro-like patches formed by interactions between the vacuole membrane… CONTINUE READING

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