Nucleus accumbens shell and core dopamine: differential role in behavior and addiction

@article{Chiara2002NucleusAS,
  title={Nucleus accumbens shell and core dopamine: differential role in behavior and addiction},
  author={Gaetano di Chiara},
  journal={Behavioural Brain Research},
  year={2002},
  volume={137},
  pages={75-114}
}
  • G. Chiara
  • Published 2002
  • Psychology
  • Behavioural Brain Research
Drug addiction can be conceptualized as a disturbance of behavior motivated by drug-conditioned incentives. This abnormality has been explained by Incentive-Sensitization and Allostatic-Counteradaptive theories as the result of non-associative mechanisms acting at the stage of the expression of incentive motivation and responding for drug reinforcement. Each one of these theories, however, does not account per se for two basic properties of the motivational disturbance of drug addiction: (1… Expand
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The role of mesoaccumbens dopamine in nicotine dependence.
  • D. Balfour
  • Psychology, Medicine
  • Current topics in behavioral neurosciences
  • 2015
There is abundant evidence that the dopamine (DA) neurons that project to the nucleus accumbens play a central role in neurobiological mechanisms underpinning drug dependence. This chapter considersExpand
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