Nucleus accumbens dopamine and the regulation of effort in food-seeking behavior: implications for studies of natural motivation, psychiatry, and drug abuse.

@article{Salamone2003NucleusAD,
  title={Nucleus accumbens dopamine and the regulation of effort in food-seeking behavior: implications for studies of natural motivation, psychiatry, and drug abuse.},
  author={John D Salamone and Merc{\'e} Correa and Susana Mingote and Suzanne M. Weber},
  journal={The Journal of pharmacology and experimental therapeutics},
  year={2003},
  volume={305 1},
  pages={1-8}
}
For several decades, it has been suggested that dopamine (DA), especially in nucleus accumbens, mediates the primary reinforcing characteristics of natural stimuli such as food, as well as drugs of abuse. Yet, several fundamental aspects of primary food reinforcement, motivation, and appetite are left intact after interference with accumbens DA transmission. Recent studies have shown that accumbens DA is involved in responsiveness to conditioned stimuli and activational aspects of motivation… CONTINUE READING
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