Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C.

@article{Jalbert1998NucleotideSA,
  title={Nucleotide structure and characterization of the murine gene encoding anticoagulant protein C.},
  author={Louise R. Jalbert and Elliot D. Rosen and A Lissens and Peter Carmeliet and D{\'e}sir{\'e} Collen and Francis J. Castellino},
  journal={Thrombosis and haemostasis},
  year={1998},
  volume={79 2},
  pages={310-6}
}
The 15,160 bp murine gene encoding anticoagulation protein C (PC) was cloned and sequenced, including 414 bp upstream of exon 1 and 80 bp downstream of the translation stop codon. Nine exons and eight introns were identified. The first exon was untranslated and contained the major transcriptional start site, the surrounding nucleotide sequence of which matched reasonably well with the consensus eukaryotic Cap element sequence. The translational initiator methionine residue was located in exon 2… CONTINUE READING