Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY.

@article{TsaiWu1991NucleotideSO,
  title={Nucleotide sequence of the Escherichia coli micA gene required for A/G-specific mismatch repair: identity of micA and mutY.},
  author={Jyy-Jih Tsai-Wu and J. Pablo Radicella and A L Lu},
  journal={Journal of bacteriology},
  year={1991},
  volume={173 6},
  pages={1902-10}
}
The Escherichia coli methylation-independent repair pathway specific for A/G mismatches has been shown to require the gene product of micA. Extracts prepared from micA mutants do not form an A/G mismatch-specific DNA-protein complex and do not contain an A/G mismatch-specific nicking activity. Moreover, a partially purified protein fraction containing both A/G mismatch-specific nicking and binding activities restores repair activity in micA mutant extracts. The DNA sequence of a 2.3-kb fragment… CONTINUE READING
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