Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune response genes

@article{McIntyre1984NucleotideSO,
  title={Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune response genes},
  author={Katherine R. McIntyre and Jonathan G Seidman},
  journal={Nature},
  year={1984},
  volume={308},
  pages={551-553}
}
Immune response genes1,2 of the murine major histocompatibility complex encode cell-surface glycoproteins that are expressed predominantly on B cells and macrophages and regulate immune responsiveness by restricting antigen recognition by T cells. The two classes of immune response molecule, termed I-A and I-E, are each comprised of two polymorphic chains (α and β), and nucleotide sequence analysis of genomic or cDNA clones has revealed that most of the amino acid differences between allelic I… CONTINUE READING

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