Nucleotide sequence of a macronuclear gene for actin in Oxytricha fallax

@article{Kaine1982NucleotideSO,
  title={Nucleotide sequence of a macronuclear gene for actin in Oxytricha fallax},
  author={Brian P. Kaine and Brian B. Spear},
  journal={Nature},
  year={1982},
  volume={295},
  pages={430-432}
}
The hypotrichous ciliated protozoan Oxytricha fallax possesses a mechanism for processing its genome into a collection of small, gene-sized, transcriptionally active sections. Macronuclear DNA is arranged as short achromosomal sections, 0.5–22 kilo-base pairs (kbp) long, while micronuclear DNA has a typical chromosomal organization1,2. Macronuclear DNA is derived from micronuclear DNA by a process of polytene chromosome fragmentation with a resultant decrease in DNA sequence complexity3,4. The… CONTINUE READING
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