Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family.

@article{Linzer1984NucleotideSO,
  title={Nucleotide sequence of a growth-related mRNA encoding a member of the prolactin-growth hormone family.},
  author={Daniel I. H. Linzer and Daniel Nathans},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1984},
  volume={81 14},
  pages={4255-9}
}
As part of the proliferative response to serum, mouse 3T3 cells produce a set of growth-related mRNAs identified by hybridization to cloned cDNAs. One of these mRNAs, which is about 1 kilobase long, appears within a few hours after stimulation of resting cells with serum or platelet-derived growth factor and reaches a high level during the transition from the G1 to the S phase of growth. This mRNA is translated in vitro into a protein of approximately 25 kilodaltons. The corresponding cloned… CONTINUE READING

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