Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs.

@article{FitzgeraldHayes1982NucleotideSC,
  title={Nucleotide sequence comparisons and functional analysis of yeast centromere DNAs.},
  author={Molly Fitzgerald-Hayes and Louise A Clarke and John R Carbon},
  journal={Cell},
  year={1982},
  volume={29 1},
  pages={235-44}
}
We determined the nucleotide sequence of DNA segments containing functional centromeres (CEN3 and CEN11) isolated from yeast chromosomes III and XI. The two centromere regions differ in primary nucleotide sequence, but contain structural features in common. Both centromere regions contain an extremely A + T-rich core segment 87-88 bp in length, flanked by two short sequences (14 bp and 11 bp) that are identical in both DNAs. These elements plus one additional 10 bp region of perfect homology… CONTINUE READING

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