Nucleotide requirements for sodium-sodium exchange catalysed by the sodium pump in human red cells.

@article{Glynn1971NucleotideRF,
  title={Nucleotide requirements for sodium-sodium exchange catalysed by the sodium pump in human red cells.},
  author={Ian M. Glynn and J F Hoffman},
  journal={The Journal of physiology},
  year={1971},
  volume={218 1},
  pages={239-56}
}
1. Resealed red cell ghosts containing a variety of nucleoside triphosphates, or a mixture of tri- and diphosphates, were allowed to lose (24)Na into a 10 mM-K medium or a K-free high-Na medium in the presence and absence of ouabain.2. Only ATP supported a ouabain-sensitive Na:K exchange in the 10 mM-K medium, or a ouabain-sensitive Na:Na exchange in the K-free medium.3. Because of ATPase and adenylate kinase activity, it is difficult to control the levels of ATP and ADP inside resealed red… CONTINUE READING

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