Nucleotide polymorphism in colicin E1 and Ia plasmids from natural isolates of Escherichia coli.

@article{Riley1994NucleotidePI,
  title={Nucleotide polymorphism in colicin E1 and Ia plasmids from natural isolates of Escherichia coli.},
  author={Margaret A. Riley and Y L Tan and J B Wang},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 23},
  pages={11276-80}
}
We examined DNA sequence polymorphism for the colicin gene clusters of seven ColE1 and six ColIa plasmids obtained from natural isolates of Escherichia coli. These gene clusters harbor levels of nucleotide diversity ranging from 0.006 (ColIa) to 0.054 (ColE1). This level of diversity is similar to that observed for chromosomally encoded E. coli genes. However, the variance associated with these estimates is severalfold higher for the plasmid-encoded genes. This increased variance may be due to… CONTINUE READING

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