Nucleotide insertion and primer extension at abasic template sites in different sequence contexts.

@article{Goodman1994NucleotideIA,
  title={Nucleotide insertion and primer extension at abasic template sites in different sequence contexts.},
  author={Myron F. Goodman and Hancheng Cai and Linda B. Bloom and Ram{\'o}n Eritja},
  journal={Annals of the New York Academy of Sciences},
  year={1994},
  volume={726},
  pages={132-42; discussion 142-3}
}
Efficiencies of insertion and extension at a single site-directed abasic lesion, X, were measured while varying 5'- and 3'-template bases adjacent to X. The preference for insertion was found to be A > G > T approximately C, with the "upstream" (3'-neighboring) template base perturbing insertion efficiencies by an order of magnitude or more. Efficiencies of… CONTINUE READING