Nucleotide excision repair polymorphisms, polycyclic aromatic hydrocarbon exposure, and their effects on sperm deoxyribonucleic acid damage and male factor infertility.

@article{Gu2010NucleotideER,
  title={Nucleotide excision repair polymorphisms, polycyclic aromatic hydrocarbon exposure, and their effects on sperm deoxyribonucleic acid damage and male factor infertility.},
  author={Ai-hua Gu and Guixiang Ji and Pengfei Zhu and Yong Zhou and Guangbo Fu and Yankai Xia and Ling Ling Song and Shoulin Wang and Xinru Wang},
  journal={Fertility and sterility},
  year={2010},
  volume={94 7},
  pages={2620-5.e1-5}
}
OBJECTIVE To evaluate the effects of polycyclic aromatic hydrocarbon (PAH) exposure and four functional genetic polymorphisms in the nucleotide excision repair pathway, alone or combined, on sperm DNA integrity and male fertility. DESIGN Retrospective case-only and case-control study. SETTING One university and three centers of clinical reproductive medicine in the Jiangsu Province of China. PATIENT(S) Six hundred twenty infertile men and 273 controls were recruited for the study… CONTINUE READING

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