Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs

@article{Andersson1996NucleotideER,
  title={Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs},
  author={Borje S. Andersson and Tara Sadeghi and Michael J. Siciliano and Randy J. Legerski and David C. Murray},
  journal={Cancer Chemotherapy and Pharmacology},
  year={1996},
  volume={38},
  pages={406-416}
}
 The objective of this study was to determine the relative importance of the first six complementation groups of the nucleotide excision repair cross-complementing genes (ERCC1–ERCC6) and the first complementation group of the X-ray repair cross-complementing genes (XRCC1), in the repair of DNA damage induced by the in vitro active cyclophosphamide (CP) derivatives 4-hydroperoxycyclophosphamide (4HC) and phosphorodiamidic mustard (PM). We compared the sensitivity of the wild-type CHO cell line… CONTINUE READING
36 Citations
66 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 36 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 66 references

Oxazaphosphorine-specific acquired cellular resistance. In: Teicher BA (ed) Drug resistance in oncology

  • NE Sladek
  • 1993
Highly Influential
4 Excerpts

Similar Papers

Loading similar papers…