Nucleotide-binding oligomerization domain containing 1 (NOD1) haplotypes and single nucleotide polymorphisms modify susceptibility to inflammatory bowel diseases in a New Zealand caucasian population: a case-control study

@article{Hbner2008NucleotidebindingOD,
  title={Nucleotide-binding oligomerization domain containing 1 (NOD1) haplotypes and single nucleotide polymorphisms modify susceptibility to inflammatory bowel diseases in a New Zealand caucasian population: a case-control study},
  author={Claudia H{\"u}bner and Lynnette R Ferguson and D. Y. Han and Martin Philpott and M L Barclay and R B Gearry and Alan F. McCulloch and Pieter S. Demmers and B. L. Browning},
  journal={BMC Research Notes},
  year={2008},
  volume={2},
  pages={52 - 52}
}
The nucleotide-binding oligomerization domain containing 1 (NOD1) gene encodes a pattern recognition receptor that senses pathogens, leading to downstream responses characteristic of innate immunity. We investigated the role of NOD1 single nucleotide polymorphisms (SNPs) on IBD risk in a New Zealand Caucasian population, and studied Nod1 expression in… CONTINUE READING