Nucleotide and deduced amino acid sequence of the rat T-cell alloantigen RT6.1.

@article{Haag1990NucleotideAD,
  title={Nucleotide and deduced amino acid sequence of the rat T-cell alloantigen RT6.1.},
  author={Friedrich Haag and F. -G. Koch and H. G. Thiele},
  journal={Nucleic acids research},
  year={1990},
  volume={18 4},
  pages={1047}
}
The rat T-cell alloantigenic system RT6 comprises two known alleles, RT6 and RT6. The respective protein products, designated RT6.1 and RT6.2, are expressed on mature peripheral T-cells of the rat, but not on thymocytes or recent thymic migrants (1—3). Diabetes-prone BB rats are deficient in RT6 expression, and this defect has been correlated with the pathogenesis of autoimmune insulin-dependent diabetes mellitus in these animals (4). We have recently reported the cDNA sequence for RT6.2 (5… CONTINUE READING