Nucleotide-amino acid interactions and their relation to the genetic code

@article{Reuben1980NucleotideaminoAI,
  title={Nucleotide-amino acid interactions and their relation to the genetic code},
  author={Jacques Reuben and Freddie E. Polk},
  journal={Journal of Molecular Evolution},
  year={1980},
  volume={15},
  pages={103-112}
}
The apparent dissociation constants of the complexes of AMP with the methyl esters of amino acids in aqueous solution exhibit good correlations with features of the genetic code and with the frequencies of occurrence of amino acid residues in proteins. Thus it is likely that chemically selective nucleotide-amino acid interactions were involved in the processes of chemical evolution that have led to the emergence of the genetic code. Based on these correlations a storage device for the… CONTINUE READING