[Nucleotide alterations of 18 S and 28 S ribosomal RNA from rat liver during carcinogenesis induced by N-nitrosomorpholine (author's transl)].

  • Michael Hümpel
  • Published 1975 in
    Zeitschrift fur Krebsforschung und klinische…

Abstract

After administration of N-nitrosomorpholine (NNM) to female Wistar-rats the ribosomal RNA (18 S and 28S rRNA) of the livers contained "abnormal" dinucleotides which were resistant against treatment with alkali or with spleen phosphodiesterase. These and further observations are discussed in view of the hypothesis that during the induction of liver tumors a… (More)

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@article{Hmpel1975NucleotideAO, title={[Nucleotide alterations of 18 S and 28 S ribosomal RNA from rat liver during carcinogenesis induced by N-nitrosomorpholine (author's transl)].}, author={Michael H{\"{u}mpel}, journal={Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology}, year={1975}, volume={84 3}, pages={311-23} }