Nucleotide Variability at Its Limit? Insights into the Number and Evolutionary Dynamics of the Sex-Determining Specificities of the Honey Bee Apis mellifera

@inproceedings{Lechner2014NucleotideVA,
  title={Nucleotide Variability at Its Limit? Insights into the Number and Evolutionary Dynamics of the Sex-Determining Specificities of the Honey Bee Apis mellifera},
  author={Sarah Lechner and Luca Ferretti and Caspar Sch{\"o}ning and Wanja Kinuthia and David Willemsen and Martin Hasselmann},
  booktitle={Molecular biology and evolution},
  year={2014}
}
Deciphering the evolutionary processes driving nucleotide variation in multiallelic genes is limited by the number of genetic systems in which such genes occur. The complementary sex determiner (csd) gene in the honey bee Apis mellifera is an informative example for studying allelic diversity and the underlying evolutionary forces in a well-described model of balancing selection. Acting as the primary signal of sex determination, diploid individuals heterozygous for csd develop into females… CONTINUE READING
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