Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein

@article{Jou1972NucleotideSO,
  title={Nucleotide Sequence of the Gene Coding for the Bacteriophage MS2 Coat Protein},
  author={Willy Min Jou and Guy Haegeman and M. Ysebaert and Walter Charles Fiers},
  journal={Nature},
  year={1972},
  volume={237},
  pages={82-88}
}
By characterization of fragments, isolated from a nuclease digest of MS2 RNA, the entire nucleotide sequence of the coat gene was established. A “flower”-like model is proposed for the secondary structure. The genetic code makes use of 49 different codons to specify the sequence of the 129 amino-acids long coat polypeptide. 
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The nucleotide sequence of the RNA of the bacteriophage MS2 was examined by computer for internal patterns and it was found that the non-coding sequences in the genome are as highly ordered, although in a different sense, as the genes themselves.
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