Nucleotide Sequence of 5S-ribosomal RNA from Escherichia coli

  title={Nucleotide Sequence of 5S-ribosomal RNA from Escherichia coli},
  author={George G. Brownlee and Frederick Sanger and Bart Barrell},
IN 1964 Rosset, Monier and Julien1 described and characterized a low molecular weight ribonucleic acid (5S RNA) that is present in the ribosomes of Escherichia coli in addition to the two larger components, the 16S and 23S RNA. It contains 120 nucleotide residues and in contrast to transfer RNA contains no “minor” bases. Using a two-dimensional fractionation procedure for the separation of nucleotides labelled with phosphorus-32 (ref. 2), we have determined the sequences of all the… 
The distribution of purine nucleotides in mu 2 viral ribonucleic acid.
The distribution of purine nucleotide sequences that might reasonably occur by chance in an RNA molecule of finite length was calculated and compared with the observed distribution in µ2 viral RNA.
Characterization of 10S RNA: A new stable RNA molecule from Escherichia coli
10S RNA cannot be processed by cell extracts to tRNA-sized molecules and does not bind significantly to ribosomes, hence it is unlikely to be a tRNA precursor or an mRNA.
Nucleotide sequences of accessible regions of 23S RNA in 50S ribosomal subunits.
Nucleotide sequences around kethoxal-reactive guanine residues of 23S RNA in 50S ribosomal subunits have been determined and one of the exposed sites in23S RNA has a sequence which is complementary to the invariant GT psi CR sequence in tRNA.
Structure and function of 5S and 5.8 S RNA.
  • V. Erdmann
  • Biology
    Progress in nucleic acid research and molecular biology
  • 1976
Processing of the ribonucleic acid in the large ribosomal subunits of Urechis caupo.
No intact 26SRNA could be detected in polysomes; this indicates that the conversion of the 26S RNA to the 17S and 17.5S RNAs may be required to produce large ribosomal subunits capable of participating in protein synthesis.
Studies on 5 s RNA conformation by partial ribonuclease hydrolysis.
  • B. Jordan
  • Biology, Chemistry
    Journal of molecular biology
  • 1971


Nucleotide Sequence of a Yeast Tyrosine Transfer RNA
The evidence indicates that the sequence containing guanosine, pseudouridine, and adenosine in the middle of the polynucleotide chain is the anticodon.
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA.
The present contains a brief account of the work leading to the elucidation of the nucleotide sequence of yeast phe-tRNA.
Structure of a Ribonucleic Acid
The complete nucleotide sequence of an alanine transfer RNA, isolated from yeast, has been determined. This is the first nucleic acid for which the structure is known.
The structures of two serine transfer ribonucleic acids.