Nucleotide-Dependent Degradation of Nucleic Acids by DNA and RNA Polymerases

Abstract

The review considers two reactions discovered recently: (1) excision of the 3′-terminal nucleotide from the nascent DNA strand in the presence of relatively high concentrations of noncomplementary r/dNTPs or r/dNDPs (pseudopyrophosphorolysis), which is catalyzed by various DNA polymerases (DNAPs), and (2) excision of the 3′-terminal nucleotide from the… (More)
DOI: 10.1023/B:MBIL.0000043938.36981.7d

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