Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling

@article{Boissan2014NucleosideDK,
  title={Nucleoside diphosphate kinases fuel dynamin superfamily proteins with GTP for membrane remodeling},
  author={M. Boissan and Guillaume Montagnac and Q. Shen and L. Gripari{\'c} and J. Guitton and M. Romao and N. Sauvonnet and T. Lagache and I. Lascu and G. Raposo and C. Desbourdes and U. Schlattner and M. Lacombe and S. Polo and A. M. van der Bliek and A. Roux and P. Chavrier},
  journal={Science},
  year={2014},
  volume={344},
  pages={1510 - 1515}
}
Supplying power: Right time, right place Cell membranes are very flexible and easily molded to shape; however, to physically pinch off a membrane vesicle from a membrane tube still requires power. A type of molecular machine known as dynamin is involved in this sort of membrane remodeling. Dynamins use guanosine triphosphate (GTP) rather than the more commonly used cellular energy source adenosine triphosphate to work. Boissan et al. now show that two separate dynamins found in the cytoplasm or… Expand
Onsite GTP fuelling via DYNAMO1 drives division of mitochondria and peroxisomes
Dynamics of the nucleoside diphosphate kinase protein DYNAMO2 correlates with the changes in the global GTP level during the cell cycle of Cyanidioschyzon merolae
  • Yuuta Imoto, Y. Abe, +4 authors Y. Fujiki
  • Chemistry, Medicine
  • Proceedings of the Japan Academy. Series B, Physical and biological sciences
  • 2019
Mammalian Homologue NME3 of DYNAMO1 Regulates Peroxisome Division
Molecular Basis of Mitochondrial and Peroxisomal Division Machineries
Nucleoside diphosphate kinases (NDPKs) in animal development
Modulation of cytoskeletal dynamics by mammalian nucleoside diphosphate kinase (NDPK) proteins
Structure, Folding and Stability of Nucleoside Diphosphate Kinases
The membrane remodeling protein Pex11p activates the GTPase Dnm1p during peroxisomal fission
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 34 REFERENCES
Dynamin: functional design of a membrane fission catalyst.
...
1
2
3
4
...