Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B.

@article{Reijnders2010NucleostideAO,
  title={Nucleos(t)ide analogues only induce temporary hepatitis B e antigen seroconversion in most patients with chronic hepatitis B.},
  author={Jurri{\"e}n G P Reijnders and Moniek J Perquin and Ningping Zhang and Bettina E Hansen and Harry L. A. Janssen},
  journal={Gastroenterology},
  year={2010},
  volume={139 2},
  pages={491-8}
}
BACKGROUND & AIMS Inconsistencies in results and guideline recommendations regarding the durability of nucleos(t)ide analogue-induced hepatitis B e antigen (HBeAg) seroconversion require clarification. We studied the long-term durability of nucleos(t)ide analogue-induced HBeAg seroconversion in patients with chronic hepatitis B virus (HBV) infection. METHODS We performed a single-center cohort study of 132 HBeAg-positive patients who had received nucleos(t)ide analogue therapy. RESULTS… CONTINUE READING

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