Nucleophilic reactivities of the anions of nucleobases and their subunits.

@article{Breugst2012NucleophilicRO,
  title={Nucleophilic reactivities of the anions of nucleobases and their subunits.},
  author={Martin Breugst and Francisco Corral Bautista and Herbert Mayr},
  journal={Chemistry},
  year={2012},
  volume={18 1},
  pages={
          127-37
        }
}
The kinetics of the reactions of different heterocyclic anions derived from imidazoles, purines, pyrimidines, and related compounds with benzhydrylium ions and structurally related quinone methides have been studied in DMSO and water. The second-order rate constants (log k(2)) correlated linearly with the electrophilicity parameters E of the electrophiles according to the correlation log k(2) = s(N)(N+E) (H. Mayr, M. Patz, Angew. Chem. 1994, 106, 990-1010; Angew. Chem. Int. Ed. Engl. 1994, 33… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-3 OF 3 REFERENCES

Angew . Chem . 1994 , 106 , 990 – 1010

T. Singer, A. R. Ofial, H. Mayr, M. Patz
  • Pure Appl . Chem .
  • 2005

For a comprehensive listing of nucleophilicity parameters N, sN and electrophilicity parameters E, see http://www.cup.uni-muenchen.de/oc/mayr/DBintro.html

H. Mayr, T. Bug, +9 authors J. Am
  • Angew. Chem. Int. Ed
  • 2001
VIEW 1 EXCERPT

Exploring QSAR - Hydrophobic, Electronic, and Steric Constants

C. Hansch, A. Leo, D. Hoekman
  • American Chemical Society,
  • 1995
VIEW 1 EXCERPT