Nucleolus disassembly in mitosis and apoptosis: dynamic redistribution of phosphorylated-c-Myc, fibrillarin and Ki-67.

@article{Soldani2006NucleolusDI,
  title={Nucleolus disassembly in mitosis and apoptosis: dynamic redistribution of phosphorylated-c-Myc, fibrillarin and Ki-67.},
  author={Cristiana Soldani and Maria Grazia Bottone and Carlo Pellicciari and A. Ivana Scovassi},
  journal={European journal of histochemistry : EJH},
  year={2006},
  volume={50 4},
  pages={273-80}
}
The nucleolus may undergo disassembly either reversibly during mitosis, or irreversibly in apoptosis, thus allowing the redistribution of the nucleolar proteins. We investigated here by immunocytochemistry the fate of three representative proteins, namely phosphorylated c-Myc, fibrillarin and Ki-67, and found that they behave independently in both processes: they relocate in distinct compartments during mitosis, whereas during apoptosis they may either be cleaved (Ki-67) or be extruded into the… CONTINUE READING

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References

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Showing 1-10 of 32 references

The nucleolus during the cell cycle

  • M Thiry, G. Goessens
  • Heidelberg, Germany: Springer-Verlag GmbH & Co KG…
  • 2004
Highly Influential
5 Excerpts

Extrusion of nuclear protein during apoptosis

  • C Pellicciari, MG Bottone, C Soldani, L Vecchio, M. Biggiogera
  • Scovassi AI, ed. Apoptosis. Kerala, India…
  • 2005
Highly Influential
6 Excerpts

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