Nucleolin protects macrophages from oxLDL-induced foam cell formation through up-regulating ABCA1 expression.


Our recent studies have indicated that nucleolin, as a multifunctional RNA-binding protein, exerts protective effects in the myocardial cells and endothelial cells under the condition of oxidative stress. However, the function of nucleolin and its potential mechanism in macrophage-derived foam cell formation remain largely unexplored. ApoE-/- mice were fed… (More)
DOI: 10.1016/j.bbrc.2017.03.047