Nucleolar organizer regions of megakaryocytes in chronic myeloproliferative disorders

  title={Nucleolar organizer regions of megakaryocytes in chronic myeloproliferative disorders},
  author={Andr{\'a}s Matolcsy and Roland G. Nador and Edit W{\'e}ber and Tibor K{\'o}nya},
  journal={Virchows Archiv A},
To study megakaryocyte activation, the argyrophilic staining method of nucleolar organizer regions (AgNOR) has been applied to decalcified bone marrow biopsies of 16 individuals with no haematopoietic disorders and 59 patients with chronic myeloproliferative disease. Of the 59 patients, 18 had chronic myeloid leukaemia (CML), 21 chronic megakaryocytic granulocytic myelosis (CMGM), 13 polycythaemia vera (PV) and 7 essential thrombocythaemia (ET). The AgNOR number of megakaryocytes in CML was… CONTINUE READING


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Chronic myeloproliferative disorders in bone marrow biopsies.

Pathology, research and practice • 1990
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