Nucleofection is the most efficient nonviral transfection method for neuronal stem cells derived from ventral mesencephali with no changes in cell composition or dopaminergic fate.

@article{Cesnulevicius2006NucleofectionIT,
  title={Nucleofection is the most efficient nonviral transfection method for neuronal stem cells derived from ventral mesencephali with no changes in cell composition or dopaminergic fate.},
  author={Konstantin Cesnulevicius and Marco Timmer and Maike Wesemann and Tobias Thomas and Tanja Barkhausen and Claudia B. Grothe},
  journal={Stem cells},
  year={2006},
  volume={24 12},
  pages={2776-91}
}
Neuronal progenitor cells (NPCs) play an important role in potential regenerative therapeutic strategies for neurodegenerative diseases, such as Parkinson disease. However, survival of transplanted cells is, as yet, limited, and the identification of grafted cells in situ remains difficult. The use of NPCs could be more effective with regard to a better survival and maturation when transfected with one or more neurotrophic factors. Therefore, we investigated the possibility of transfecting… CONTINUE READING

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