Nucleobases bind to and stabilize aggregates of a prebiotic amphiphile : a viable mechanism for the emergence of protocells


Primordial cells presumably combined RNAs, which functioned as catalysts and carriers of genetic information, with an encapsulating membrane of aggregated amphiphilic molecules. Major questions regarding this hypothesis include how the four bases and the sugar in RNA were selected from a mixture of prebiotic compounds and co-localized with such membranes… (More)

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