Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses

Abstract

Tissues used for clinical diagnostics are mostly formalin-fixed and paraffin-embedded (FFPE) which provides many advantages. However, the quality of the obtained nucleic acids (NA) is reduced and this turns out to be a challenge for further molecular analyses. Although the spectrum of analyses of NA extracted from FFPE tissue has increased, the standard… (More)
DOI: 10.1007/s00428-011-1184-9

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Cite this paper

@article{Ludyga2011NucleicAF, title={Nucleic acids from long-term preserved FFPE tissues are suitable for downstream analyses}, author={Natalie Ludyga and Barbara Gr{\"{u}nwald and Omid Azimzadeh and Sonja Englert and Heinz Hoefler and Soile Tapio and Michaela Aubele}, journal={Virchows Archiv}, year={2011}, volume={460}, pages={131-140} }