Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study.


The critical functions of the HIV-1 nucleocapsid protein NCp7 in genomic RNA packaging and reverse transcription, essentially rely on interactions with nucleic acids. A significant progress in the knowledge of these interactions has been recently achieved with the NMR-derived structures of NCp7 derivatives in complex with two short sequences of the HIV-1… (More)


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